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Bioreactor Monitoring Using Non-Invasive Raman Spectroscopy
Raman spectroscopy is a non-destructive, non-invasive technique that is an excellent alternative to traditional process-monitoring methods that require sampling. Raman provides real-time information on the state of the bioreactor. In our previous blog post – St. Patrick’s Day at Beer&W Tek! we demonstrated how the fermentation process is monitored using an i-Raman EX, a 1064-nm laser laboratory instrument, with RIS101 Sapphire Ball Immersion Shaft. In this post, we take the next step of performing non-invasive, stand-off monitoring of the brewing process with a RTS202 Stand-off lens (Figure 1). This allows us to gather real-time information on the state of the bioreactor without the risk of disruption or contamination. Continue reading
Steeping into the World of Tea with Raman
Raman spectroscopy is a promising technique in food science due to its ability to provide rapid and non-destructive analysis of samples. For instance, we have previously explored the Raman spectra of olive oils using the B&W Tek i-Raman® Plus-785 system (Fast Ingredient Analysis of Edible Oils Using a Portable Raman Spectrometer). Regular Raman spectroscopy can be applied to investigate properties of traditional/herbal tea, and when Raman is coupled to SERS technology it can be used to detect trace pesticides (ug level) on tea leaves (Trace Detection of Paraquant in Tea Leaves)… Continue reading
Panning for Gemstones: The Raman Rush
Fall is a season of harvest and festivals, which makes it an ideal time to get outside while the weather … Continue reading
Veggie burger or Beef burger? Let Raman tell you!
You may have heard of vegetarian-friendly foods like cauliflower burgers and the Impossible Burgers for example. Both are created to … Continue reading
Quantitative analysis of Milkfat content
Milk from cattle and other domestic livestock has been an important food source for humans for thousands of years. The … Continue reading
St. Patrick’s Day at Beer&W Tek!
HAPPY ST. PATRICK’S DAY! St. Patrick’s Day (March 17th) has been popularized worldwide as a time to celebrate by wearing … Continue reading
International Day of Women and Girls in Science 2022
Friday, February 11th was International Day of Women and Girls in Science 2022. This day was declared in 2015 as … Continue reading
Using Portable Raman Instrumentation to Make the Wintertime Safer
The winter season can be one of the most beautiful times of the year. Unfortunately, along with the freshly fallen … Continue reading
Using Raman to Choose the Ingredients for Santa’s Treats
Happy Holidays from Your Spectroscopy Partner! In the USA, putting out a plate of cookies and a glass of milk … Continue reading
1064 nm Raman Excitation of Fluorescent Pumpkin Seed Oil
Happy Halloween! Jack-O-Lanterns, pumpkins with ghoulish faces placed in front of homes, have been a symbol of Halloween for centuries1. Because … Continue reading
Raman Spectroscopy of Italian Cheeses
September is National Italian Cheese Month! Did you know that there are over 450 varieties of Italian cheeses? The most … Continue reading
Raman Spectroscopy and Its Use in Monitoring Olive Oil Adulteration
June 1st is National Olive Day! To honor the occasion, we thought we would highlight some of the ways that … Continue reading
Celebrating Earth Day: Portable Raman Spectroscopy for a SERS-Based Screening of Freshwater Contamination
As we celebrate Earth Day 2021 we would like to focus on Raman studies done to protect our environment. There … Continue reading
Surface-Enhanced Raman Spectroscopy-Based Detection of SARS-CoV-2 Antibodies with a Portable Raman Spectrometer
In recent years, both portable Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) have become crucial techniques in medical diagnostics and … Continue reading
The History of National Science Day
In India, February 28th is celebrated as National Science Day. India’s Ministry of Culture describes1 the purpose of National Science … Continue reading
Recipes with Raman
Many of us have spent more time in the kitchen in the past year than usual, (re)discovering our culinary skills … Continue reading
The Importance of Relative Intensity Correction of Raman Data
As portable Raman technology becomes more prevalent especially among pharmaceutical businesses and within defense and security fields, so too does … Continue reading
Direct Analysis of Tapestry Dyes with Raman Spectroscopy
Tapestry is very important to the history of woven textiles. Egyptian cave paintings of weavers date them back to 3000 … Continue reading
Raman vs SERS…What’s the Difference?
If you’ve ever had a conversation with a Raman spectroscopist about the feasibility of a low-concentration sensing application, chances are … Continue reading
Transmission Raman and Content Uniformity Testing
Content uniformity testing is a standard pharmaceutical test to ensure the active pharmaceutical ingredient (API) content in solid dosage forms … Continue reading
STRam®: 1064 Making Waves
Raw pharmaceutical materials are frequently packaged within polyethylene bottles, or Kraft paper sacks in single or multiple layers. Properly identifying … Continue reading
Historic Stamps: Cracking down on counterfeits with Raman
Historical stamps are cultural heritage objects that provide an invaluable amount of historical information. Holding a high monetary value as … Continue reading
Portable Spectrometers for Raw Material ID
Portable spectrometers are designed for maximum ease-of-use for onsite materials analysis and testing. They have been adapted from a suite … Continue reading
Thin Film Analysis with B&W Tek
Modern engineering is increasingly concerned with device miniaturization and the exploitation of materials at smaller dimensions than ever. At the … Continue reading
Counterfeit Analysis: Which Spectroscopic Method Works Best?
Counterfeit analysis encompasses a broad range of tools used to distinguish adulterated substances from the genuine article. In border control … Continue reading
Key Principles of Carbon Analysis
Carbon (C) is one of the most ubiquitous elements ever discovered, forming a fundamental component of all living things and … Continue reading
Interview: Peter Muller Talks about Using the i-Raman Plus for Mineral Identification
Raman spectroscopy is growing in popularity as a tool for mineral identification due to its heightened sensitivity to chemical structures … Continue reading
Webcast – Quantitative At-Line Portable Raman for Process Control: Development, Validation, and Implementation with a Pharmaceutical Example
In this webinar, viewers will get an inside look at how portable Raman is being developed for at-line quantitation of nonionic surfactants in pharmaceutical formulations at Eli Lilly. Continue reading
Smithsonian App Note: Raman Analyzes Aviation Glass
These two research articles published by the Smithsonian Institution feature our MiniRam II portable Raman spectrometer. One article discusses the research of the co-evolution of plastics and early human flight, the second specifically explores the working distance when identifying plastics, particularly those of the early 20th century. Continue reading
Roundtable: PAT
This roundtable discussion, published by European Pharmaceutical Review, discusses PAT’s current and future role in pharmaceuticals. Continue reading
Raman Makes An Impact in Plastic Toy Safety, As Well As Security & PAT
This application note, published in Spectroscopy Asia, discusses how Raman quantitative and semi-quantitative analysis makes an impact in three different applications: Security, Plastic Toy Safety, and PAT (Process Analytical Technology). Continue reading
Raman Uncovers Prehistoric Paintings
This application note focuses on rock art paintings in five rock art sites in the eastern Iberian Peninsula. Each of these sites presents outstanding difficulties of analysis by Raman spectroscopy, the most prevalent being crusts that mask Raman signals from the pigments of the paint recipe. Continue reading
Improving Forensic Investigations using Raman Spectroscopy
This application note in Spectroscopy Magazine discusses the benefits of using portable and handheld Raman spectroscopy (particularly the TacticID handheld Raman spectrometer) to identify forensic and homeland security-related samples. Continue reading
Roundtable Discussion on Raman
In a roundtable discussion with European Pharmaceutical Review, B&W Tek’s Chief Operating Officer, Jack Zhou, answers questions about the progress of Raman technology as it pertains to the pharmaceutical industry, as well as potential developments to Raman devices and the improvement of results they could provide. Continue reading
Using Raman to Identify Contaminated Alcohol
This article, published in Spectroscopy magazine, discusses using portable Raman spectroscopy to identify and quantify methanol in contaminated liquor. We discuss why portable Raman spectroscopy is the ideal choice for screening methanol-laced rum and other types of adulteration. Continue reading
New Article in the Journal of Raman Spectroscopy
This research article discusses using surface-enhanced Raman spectroscopy (SERS) to detect & identify traces of pentaerythritol tetranitrate (PETN), ethylene glycol dinitrate (EGDN), cyclotrimethylene-trinitramine (RDX) & trinitrotoluene (TNT) using commercially available substrates… Continue reading
App Note: Quantitative Analysis of Tertiary Mixtures
Application note on using Raman spectroscopy to develop a quantitative calibration model to determine the glucose, fructose and sucrose concentrations in a tertiary aqueous mixture. Continue reading
Tip of the Week: 05/14
For field applications like geological or archeological studies, use DC power on any B&W Tek portable Raman spectrometer for battery operation mode. Continue reading
Educational Video Series: Episode 6 – Raman Spectroscopy
In this season finale episode of B&W Tek’s Educational Video Series we discuss Raman. Our discussion will include an introduction … Continue reading
Raman Spectroscopy Tackles Pharmaceutical Raw Materials
Today’s Raman instrumentation is faster, more rugged and less expensive, and advances in component miniaturization have led to the design of high-performance, portable, handheld devices. These handheld devices are particularly well-suited for pharmaceutical applications. Continue reading
Analytical Instrumentation Gets Faster, Smaller, and Easier to Use
Drug Development & Delivery magazine recently contacted B&W Tek to discuss how we’re developing devices that address key trends in today’s pharmaceutical industry: the need for faster sample prep, more user-friendly equipment, and smaller but more sophisticated instruments. Continue reading
Tradeshow: Pittcon 2013
B&W Tek is very excited to share our most recent technological advances at Pittcon this year! Since last year’s show, we’ve made some really exciting developments in our products and services! Continue reading
i-Raman Plus: Enhanced High Resolution Raman System
We are proud to announce the i-Raman® Plus portable Raman spectrometer – an enhanced version of our award winning i-Raman, now powered by our innovative smart spectrometer technology. Continue reading
BiOS & Photonics West 2013
B&W Tek is very excited to share our most recent technological advances at Bios and Photonics West this year. Since last year’s show, we’ve made some really exciting developments in our products and services! Continue reading
Tip of the Week: 12/10
If you’re seeing a significant amount of fluorescence in your Raman signal, use B&W Tek’s proprietary airPLS background correction. Continue reading
Tip of the Week: 11/29
When choosing the correct Raman spectrometer for your lab, it is important to consider the overall utility of the system. Continue reading
Tip of the Week: 10/10
When measuring sources of unknown intensity, it is often useful to use the “auto-integration” function in BWSpec… Continue reading
E-book: Portable Raman Enters a New Era
In this e-book, see how Raman has gained new reach within the pharmaceutical industry, due in large part to improved performance, better functionality and ease of use, and easy transfer of spectral information and libraries… Continue reading
Webcast: Raman Spectroscopy for Biomedical Diagnostics
On Wednesday, 10/17/12 at 1pm (EDT), we will be sponsoring a webcast given by Dr. Jennifer Granger, hosted by Spectroscopy Magazine… Continue reading
Tip of the Week: 8/22
The BAC151A Raman Video Microscope is designed specifically for the head to be removed from the stage and attached to … Continue reading
App Note: In-situ Monitoring of Polymorphic Transitions using Raman
Application note on the benefits of Raman spectroscopy to identify polymorphs in the pharmaceutical industry.… Continue reading
Webcast: Spectroscopy in Medicine & Biology
On Tuesday, 6/19/12 at 11am EDT, we will be sponsoring a webcast given by Dr. Robert Alfano, hosted by BioOptics World… Continue reading
App Note: Raman for Identification and Characterization of Polymers
Application note on the benefits of Raman spectroscopy for the identification and characterization of polymers… Continue reading
Patent Awarded: Fiber Spectroscopic Probe Mounted onto Microscope
Spectroscopic probe directly mountable to a microscope to add spectroscopic functionality with minimal alteration to the optical path… Continue reading
App Note: Fundamentals of Raman Spectroscopy
App note on the fundamentals of Raman spectroscopy based on the popular webcast given by Travis Thompson, transcribed by LFW… Continue reading
App Note: Quantitative Raman Analysis
Chemometric modeling to determine concentrations of methanol in tertiary mixtures using a high resolution portable Raman spectrometer… Continue reading
BWSpec 4.00: Spectral Data Acquisition Software
Announcing new improvements including spectral management system, spectrum list panel and 64 bit compatibility… Continue reading
Webcast: Raman Analysis of Polymers and Additives
On Wednesday, 3/7/12 at 1pm (ET) we will be hosting a webcast given by Travis Thompson and Henryk Herman, hosted by Spectroscopy… Continue reading
BAC200: Raman Micro Lensed Probe
We are proud to introduce the first Raman probe capable of delivering high performance in a diameter of less than 4mm… Continue reading
Raman Knowledge: Your Guide to Fundamentals of Raman Spectroscopy
We’ve provided a full technical section on the theory of Raman scattering as well as the components of a Raman spectrometer… Continue reading
PolymerIQ: Raman Polymer Identification and Quantification
Announcing a revolution in fast and accurate measurements of polymers and additives, jointly developed with Gnosys Global… Continue reading
Poster: Quantitative Raman Analysis at FACSS 2011
Chemometric modeling to determine concentrations of methanol in tertiary mixtures using a high resolution portable Raman spectrometer… Continue reading
BWIQ: Chemometrics Software
Multivariate software for analysis of spectral data to discover internal relationships between spectra and response data/sample classes… Continue reading
Webcast – Fundamentals of Raman Scattering
On Thursday, 9/22/11 at 1pm (ET), we will be presenting a webcast given by Travis Thompson, hosted by LaserFocusWorld… Continue reading
Webcast: Multiple Distributed Portable Raman Spectrometers
On Tuesday, 9/27/11 at 2pm (ET), we are sponsoring a webcast given by John Kauffman of the FDA Division of Pharmaceutical Analysis… Continue reading
GemRam: Raman Gemstone Identification System
Debuting the GemRam, a new, portable Raman spectrometer dedicated to the verification and identification of gemstones… Continue reading