pharmaceutical drugs, alcohol with iraman specrtrometer in background

Counterfeit

Raman spectroscopy is well recognized as an analytical tool for the discrimination of similar molecules. Because of this, counterfeit substances such as diluted edible oils and counterfeit prescription drugs can be measured and controlled before they reach the consumer, and hopefully even sooner to reduce unnecessary production costs. Likewise, product tampering such as diethylene glycol in glycerin, melamine in milk powder and methanol-contaminated liquor can be identified. Similar molecules such as ethanol and methanol, as well as falsely labeled prescription drugs can be analyzed on-site in order to confirm the chemical composition to ensure safety and reliability in the products we use every day.

What makes Raman ideally suited for this particular application over comparative technologies such as FTIR is the ability to measure through optically transparent containers and its insensitivity to interference from water. Portable Raman spectrometers can be used not only for the identification of adulterants, but also for providing quantitative results. This technique can be expanded to other types of adulteration; even including water dilution of alcohol.

Products

NanoRam®

Handheld Raman Spectrometer

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i-Raman®

High Resolution TE Cooled Fiber Optic Raman System

i-Raman® high resolution Raman spectrometer by B&W Tek

i-Raman® Plus

Highly Sensitive, High Resolution Fiber Optic Raman System

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i-Raman® EX

1064nm Fiber Optic Raman System

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NanoLIBS®

Handheld LIBS Analyzer for the Pharmaceutical Industry

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Application Notes

Law enforcement personnel, laboratory technicians, crime scene investigators and many others face a significant challenge for identification of materials in a forensic investigation, as they must routinely examine materials such as gun powder residue, drugs of abuse, hair sampling, chemical precursors and more. In these cases, technologies such as Raman spectroscopy can be successfully used for cursory identification of multiple forensic sample types either directly in the field or in the lab.
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Dispersive Raman spectroscopy has increasingly been implemented for material identification due to its portability and sampling flexibility. When choosing a Raman instrument, a primary concern is the wavelength of the laser that is integrated into the Raman spectrometer system. Though the Raman shift of any material is only related to the material’s specific chemical structure and is independent of the excitation wavelength, different wavelengths have their strengths and weaknesses.
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Over the past several years, an alarming trend has become evident, highlighting serious issues related to contaminated alcohol within the European Union. In September 2012 the Czech Republic officially banned the sale of hard liquor after 20 people died from the consumption of methanol-laced spirits. After an exhaustive study, the Czech Republic turned to the use of portable Raman spectroscopy to quantify methanol in contaminated spirits.
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This webinar evaluates the Raman spectral library of finished products, with an emphasis on method specificity and counterfeit identification, and demonstrates use on a handheld instrument.
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In this presentation, Katherine Bakeev discusses the growing global issue of counterfeit medicines and how our NanoRam handheld Raman spectrometer offers quick and easy testing for the detection of these counterfeit medicines.
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