Raw Material ID
Raw material identification and verification is a regulatory requirement for pharmaceutical manufacturers. The use of Raman outside of pharmaceutical applications is growing rapidly. Raman instruments provide a molecular fingerprint of samples for nondestructive identification and verification of materials such as active pharmaceutical ingredients (APIs), excipients, intermediates, and finished products.
Raw Material ID Applications
While best known for its use on the loading dock of a pharmaceutical manufacturing site, Raman continues to expand into new markets. From chemical plants to polymers and plastics, read the following application notes to see how Raman raw material identification measurements are performed.
Using Handheld Raman to Reduce Risks in Materials Used for Manufacturing
Raman spectroscopy is a valuable tool for providing rapid, specific analysis for identifying raw materials, thus reducing the risk of using substandard or incorrect materials in manufacturing. The utility of handheld Raman increases productivity and the ability to do complete testing without creating bottlenecks in the production process.
Cost & Benefits of Handheld Raman for Quality Control Testing of Incoming Raw Materials
Handheld Raman solutions have improved the ability to complete incoming raw material testing without sample preparation. The NanoRam handheld Raman contributes to increased quality testing with a cost-effective technology used at the point of receipt, thus minimizing steps to material acceptance, giving a high return on investment (ROI).
Fast Ingredient Analysis of Edible Oils
In this application note, the main ingredients of olive oil, camellia oil, arachis oil, sunflower seed oil, and colza oil are analyzed using a portable Raman spectrometer combined with chemometrics software.
Sampling Guidelines for Handheld Raman Measurements
Handheld Raman tests raw materials for different sample types and forms. Using optimized sampling accessories enhances the utility of handheld Raman without compromising data quality or complicating testing.
Raman Spectroscopy as a Tool for Process Analytical Technology
This article demonstrates the utility of portable Raman spectroscopy as a versatile tool for process analytical technology (PAT) for raw material identification, in-situ monitoring of reactions in developing active pharmaceutical ingredients (APIs), and real-time process monitoring. Raw material identification is done to verify starting materials as required by PIC/S and cGMP, and can be readily done with handheld Raman.
Related Products
Raw material identification demands consistent sampling for accurate and reproducible data. Our Discover-It-Yourself systems fit on a benchtop and allow complete "fit for purpose" analyzer development. Our integrated systems and handheld Raman spectrometers take the measurement to the sample for easy, fast analysis.
Discover-It-Yourself UV-Vis and Raman
UV-Visible Discover-It-Yourself systems enable routine quality control measurements of incoming raw materials. Raman measurements can be used for verification and validation inherent to GMP requirements. DIY systems can be configured specifically for your application and sample types.
Discover-It-Yourself SystemsIntegrated Raman Systems
Our portfolio of laboratory and handheld spectrometers are a prefect fit for raw material identification in the regulated and non-regulated lab.
Raman Systems