NanoRam® – BWT-840000341
Handheld Raman Spectrometer
The NanoRam is a state-of-the-art handheld Raman instrument for nondestructive identification and verification of materials such as APIs, excipients, intermediates, & finished products. Compact and agile, the NanoRam can be used by non-technical users to rapidly identify samples in the lab, warehouse, loading dock or field, helping to eliminate quarantine areas and expedite materials through the manufacturing lifecycle. Utilizing Raman technology, non-contact analysis can be performed through transparent containers, all while maintaining the volume and integrity of the sample.
The NanoRam handheld Raman spectrometer facilitates fast and convenient transitions between sampling accessories for raw material identification through a variety of packaging. The NanoRam comes standard with the point and shoot, vial holder, bottle adaptor, and immersion probe accessories for optimal identification of different sample forms. These accessories allow you to measure through plastic and glass containers, take in situ measurements of liquids and powders, and measure larger containers only accessible from the top. Additionally, right angle, and tablet holder accessories are available to facilitate hands-free sampling . The NanoRam is operated with easy to follow, touch screen NanoRam OS (NOS) embedded software, which allows for identification and verification and library and method development. The NanoRam ID (NID) PC software provides a secure database for data and methods management, allowing customers to export data, generate and e-sign reports and transfer methods and libraries to other NanoRam units.
Raman spectroscopy is an approved method by the U.S. and European Pharmacopoeia, as well as the Pharmacopoeia of the People’s Republic of China. It is also a well-recognized method for compliance with the PIC/S GMP guide regarding 100% identity assurance for starting materials. NanoRam has performance validation tests to ensure system performance to the standards of the USP<858>, EP 2.2.48 and JP 2.26. The NanoRam is fully compliant with all governing regulations, including 21 CFR Part 11 and Part 1040.10, and can play an integral role in cGMP compliant facilities. B&W Tek offers a wide variety of services, including assistance with method and/or new library development as well as support with IQ/OQ/PQ implementation.
Intuitive Software – a user-friendly interface for both technical & non-technical users to make their job easier
Versatility – measure a variety of samples in a variety of environments and packaging with just one unit
Data Reproducibility – superior hardware ensures that results are consistent and reliable
Performance – robust multivariate algorithms guarantee accuracy when testing and identifying materials
Integrated Computer
State-of-the-art Touch Screen
The NanoRam offers unprecedented calculation power for handheld devices, employing a fast processor optimized to operate under B&W Tek’s proprietary Nanoram OS. Within seconds, it is able to process data, manage libraries of any size, and accurately identify the materials analyzed with a new level of quality from portable devices. It is designed with the capability to run almost any calculation required in day- to-day operations, without the need to download data for post-processing.
Data Quality & Reproducibility
• Robust hardware provides high quality data with low noise providing consistent and reliable results with fast measurement times. Even samples that have weak Raman signal can be identified with the NanoRam because of this high dynamic range system.
• Broad spectral range as low as 176 cm-1 for more spectral data to improve identification capabilities
• Method and library transfer between devices for company wide deployment
• User-definable methods and libraries to meet particular analysis needs
• TE cooling allows for greater stability of the instrument in environments where temperatures are highly variable.
Sampling Accessories
Easy Transition Between Sample Types
The NanoRam includes a variety of sampling accessories to assist you in the measurement of various materials in the form of liquids, gels, powders, or solids under both a laboratory setting and under demanding environmental conditions. The NanoRam is designed to facilitate fast and convenient transitions between sample adaptors.
The NanoRam comes standard with the point and shoot, vial holder, and bottle adaptor accessories. Additionally, a right angle, tablet holder, and immersion shaft are available to facilitate even more flexible sampling. These accessories allow you to measure through plastic and glass containers, take in situ measurements of liquids and powders, and measure larger containers only accessible from the top or located in difficult to reach areas. More details about individual accessories are available upon request.
Software
State-of-the-art Identification Software
The NanoRam comes standard with B&W Tek’s proprietary NanoRam OS software installed within the unit, which allows for identification and verification, library and method development, and data storage/ transfer. The NanoRam ID software is designed for use on PCs for data and methods management, allowing customers to export data and generate reports. The NanoRam ID and NanoRam OS software packages are 21CFR part 11 compliant with available IQ/OQ validation documentation for pharmaceutical customers.
Additionally, the NanoRam provides secure Wi-Fi and Ethernet synchronization capabilities with network terminals in order to optimize time and resources. NanoRam OS is capable of real time data and report transfers in order to centralize information (such as libraries, method development and final reports) in general servers.
