The i-Raman^® Prime is a high sensitivity and high throughput fully integrated Raman system with an embedded tablet computer and fiber optic probe sampling. Using a high quantum efficiency CCD array detector with deep cooling (-25°C) and high dynamic range, this portable Raman spectrometer delivers research-grade Raman capabilities including real-time quantitation and identification capabilities. The high throughput gives excellent signal to noise ratio making it possible to measure even the slightest Raman signals and detect subtle sample differences. The i-Raman Prime series features the unique combination of wide spectral coverage and high resolution, measuring down to 150 cm^-1 to up to 3400cm^-1, in a mobile design. The i-Raman Prime offers three excitations of 532, 785, and 1064 nm that can accommodate numerous applications.

The i-Raman Prime can be battery operated for easy portability, giving research grade Raman capabilities for high precision qualitative and quantitative work wherever needed. The system is optimized for use with our STRaman^® technology.

Click here to download our portable Raman product compatibility chart

Applications:

• Bioscience and Medical Diagnosis
• Pharmaceutical Analysis
• Raman Microscopy
• Process Monitoring (PAT)
• Forensic Analysis
• Geological and Mineralogical Research
• Materials Science Research
• SERS

SENSITIVE:
High sensitivity and low noise detector combined with a high-throughput spectrometer giving excellent sensitivity to detect even low concentrations and samples with weak Raman signal. The high sensitivity gives high signal-to-noise ratio needed for biological systems. Shorter integration times are achievable due to high throughput, allowing for faster measurements as needed for process monitoring.

COMPREHENSIVE:
The fiber-optic-probe based sampling gives the flexibility to make measurements in different positions for a range of sample sizes and forms. Our comprehensive package of sampling accessories, including a video microscope and lenses for stand-off measurements, provide the utmost utility for Raman analysis in the lab and the field. The i-Raman Prime is compatible for use with our STRaman® technology, featuring see-through measurement capabilities over a larger sample area.

TOUCH SCREEN INTERFACE:
The i-Raman Prime is a fully integrated system with a touchscreen tablet computer running touch-friendly software, providing material identification and real-time predictions.

The QTRam^® is a portable Transmission Raman Spectrometer powered by our patented STRaman^® technology optimized for rapid and nondestructive quantitative analysis ideal for content uniformity testing of finished products such as tablets and capsules.

The portable QTRam can be used for at-line quantitation of tablet composition, reducing the time and associated production delays that come from needing to submit samples to the laboratory for in-process and final product testing. Calibrations can be developed for multi competent testing from a single Raman spectrum.

The QTRam can be easily operated using 21CFR Part 11 compliant software for quantitative analysis on the inbuilt tablet computer, while the portable form factor allows users to use it for at-line analysis or in the lab.

Click here to download our portable Raman product compatibility chart

Applications:

• Content uniformity - ensure the dosage uniformity of the API in solid dosage finished product including tablets, capsules, and gels
• Formulation development - support QbD initiatives in quantifying API and excipient concentrations in finished dosage forms
• Counterfeit detection – calculate API quantity to ensure correct drug and correct dosage

Applications:

• Versatile STRaman^® technology with high sensitivity and high-throughput for see-through, transmission, or conventional Raman Spectroscopy
• Easy-to-use 21 CFR Part 11 compliant software for quick results and reporting
• Portability for in-line, at-line, or laboratory analysis
• Customizable sample holders to accommodate any sample dimension
• Step by step, easy to follow quantitative modeling and method development

Benefits:

• Rapid quantitative results in seconds
• Quantitative sample composition, crystallinity and polymorphic form from single measurement over large sample volume
• No sample preparation
• No consumables
• No disposal cost
• USP-recognized transmission Raman for content uniformity applications

The NanoRam-1064 is a state-of-the-art handheld Raman instrument for nondestructive identification and verification of incoming raw materials such as APIs, excipients, and intermediates. Compact and agile, the NanoRam-1064 can be used by non-technical users to rapidly identify samples in the lab, warehouse, loading dock or field, helping to eliminate quarantine areas and expedite materials through the manufacturing lifecycle. Utilizing Raman technology, analysis can be performed through transparent containers, all while maintaining the volume and integrity of the sample. The high-performance NanoRam-1064 minimizes fluorescence, so can effectively identify many more materials, even those with color. The NanoRam-1064 can differentiate different types of cellulose, polysorbate and Opadry®. The unit also offers full onboard library and method validation, saving users time when activating new methods and library entries on the device.

The NanoRam-1064 is fully compliant with all governing regulations, including 21 CFR Part 11 and Part 1040.10, and plays an integral role in cGMP-compliant facilities. The NanoRam-1064 meets the requirements of Raman spectroscopy methods including the US Pharmacopeia <858>, European Pharmacopeia 2.2.48, Japanese Pharmacopoeia 2.26, as well as the People’s Republic of China Pharmacopeia Guidelines on Raman Spectroscopy. Raman is a well-recognized technology for compliance with the PIC/S & GMP guidelines regarding 100% identity assurance for starting materials. B&W Tek offers a wide variety of services, including method and/or new library development support as well as IQ/OQ/PQ implementation services.

Features:

• Easy Operation for Non-Technical Users
• Touch screen interface with simple 1-touch workflow
• Easy single-handed operation
• Batch mode for quick testing of multiple containers
• Interface available in multiple languages
• Robust sample identification and verification methods
• On-board method and library validation
• On-board instrument performance validation and calibration
• Camera for quick method selection and product information entry

The award-winning STRam^® portable Raman system delivers rapid material identification capabilities through a variety of barrier layers and packaging previously impenetrable with Raman. The system design unites a high throughput spectrometer, specialized sampling optics and advanced algorithms in a compact Raman system with embedded tablet computer. The STRam and STRam-1064, operating with 785 and 1064-nm Raman excitation respectively, can identify materials through multiple layers of packaging to meet your application needs.

With our patented technology, you can use the STRam to identify samples inside opaque packages. The STRam collects Raman signal generated underneath diffusive top layers so you can identify material inside visually opaque barriers such as white plastic bottles, paper envelopes, tablet coatings, and highly fluorescent Kraft paper. This removes the need to open containers and have any direct exposure with the material, thus maintaining package and sample integrity, and increasing operator safety.

The STRam design features a large sampling area and sampling depth and minimized power density, so you can measure samples that can be challenging for conventional focused Raman spectroscopy.

Click here to download our portable Raman product compatibility chart

Applications:

• Through-Package Material Inspection
• Customs and Logistics Package Inspection
• Pharmaceutical Raw Material Identification
• Narcotics Detection
• Art and Archaeological Study
• Bioscience and Medical Analysis
• Forensic Analysis
• Geological and Mineralogical Research
• Material Science Research

SENSITIVE:

The system design enhances the signal at a greater depth so that samples inside opaque containers can be identified without the signature of the top layers overwhelming the sample signature. The system combines a high-throughput spectrometer, a high sensitivity and low noise detector, a specialized sample probe, and advanced identification algorithms.

VERSATILE:

The system provides versatility for see-though measurements through barriers and across a large sampling area while allowing low power density in measuring sensitive samples. Specialized adaptors can easily be attached for focused measurement directly on a sample. The STRam can be used for Raman analysis of samples ranging from those in packages to sensitive energetics or biological samples, and its large spot size gives greater reproducibility of heterogeneous sample measurements.

TOUCH SCREEN INTERFACE:

The STRam is a fully integrated system with a tablet computer running 21CFR part 11 compliant software for through-barrier-layer material identification. With optional battery operation for easy portability, the system provides research-grade, high-sensitivity Raman capabilities wherever needed.

The i-RAMAN® EX is part of our award-winning line of i-Raman portable Raman spectrometers featuring a 1064 nm version of our patented CleanLaze® excitation laser. Using a high-sensitivity InGaAs array detector with deep TE cooling, high dynamic range and a highthroughput spectrograph design, this portable Raman spectrometer delivers a high signal-to-noise ratio without inducing autofluorescence, making it possible to measure a wide range of natural products, biological samples such as cell cultures, and colored samples.

The i-RAMAN® EX provides a spectral coverage range from 100-2500 cm-1, enabling you to measure the entire fingerprint region. The system’s small footprint, lightweight design, and low power consumption provide research-grade Raman capabilities anywhere. The i-RAMAN® EX comes equipped with a fiber-optic probe and an XYZ-positioning-stage probe holder. It can be used with a range of sampling accessories to facilitate measurements of samples in many forms. For expanded analysis capabilities, it can be used with Vision software as well as BWIQ® multivariate analysis software and BWID® identification software. With the i-RAMAN® EX, a high precision qualitative and quantitative Raman solution without fluorescence is at your fingertips.

Click here to download our portable Raman product compatibility chart

APPLICATIONS:

• Forensic Analysis, Including Narcotics
• Bioscience & Biomedical Diagnostics
• Chemical Warfare Agent Detection
• Pharmaceutical Material Analysis
• Polymer & Chemical Analysis
• Environmental Science
• Explosives Detection
• Petroleum Analysis
• Natural Product Testing

FEATURES:

• High-Throughput Spectrograph for Faster Signal Collection
• Patented CleanLaze® Technology for Laser Stabilization
• Fiber Optic Coupling for Convenient Sampling
• 1064nm Excitation to Minimize Fluorescence
• Adjustable Laser Power

COMPREHENSIVE:

Our comprehensive package of sampling accessories for measuring solid and liquid samples provide you the utmost utility right out of the box.

QUANTITATIVE:

Quantitative analysis can be done with Vision software and with the BWIQ® multivariate data analysis software, each with powerful algorithms behind intuitive user interfaces and graphical displays of analysis results.

The i-Raman^® Plus is part of our award winning line of i-Raman portable Raman spectrometers powered by our innovative smart spectrometer technology. Using a high quantum efficiency CCD array detector with deeper cooling and high dynamic range, this portable Raman spectrometer delivers an improved signal to noise ratio for up to 30 minutes, making it possible to measure weak Raman signals. The i-Raman Plus features the unique combination of wide spectral coverage and high resolution with configurations measuring from 65 cm^-1 to up to 4200 cm^-1, enabling you to measure stretching bands around 3100 cm^-1. The system’s small footprint, lightweight design, and low power consumption provide research grade Raman capabilities you can take your 532 or 785 excitations anywhere! The i-Raman Plus comes standard with a fiber optic probe, and can be used with a cuvette holder, a video microscope, an XYZ positioning stage probe holder and our proprietary BWIQ^® multivariate analysis software and BWID^® identification software. With the i-Raman Plus, a high precision qualitative and quantitative Raman solution is at your fingertips.

Click here to download our portable Raman product compatibility chart

Applications:

• Art & Archaeology
• Bioscience and Medical Diagnosis
• Polymers and Chemical Processes
• Semiconductor & Solar Industry
• Geology and Mineralogy
• Pharmaceutical Industry
• Environmental Science
• Raman Microscopy
• Forensic Analysis
• Gemology
• Teaching
• Quality Control
• General Research

SENSITIVE:

High quantum efficiency CCD array detector with deeper cooling and high dynamic range

COMPREHENSIVE:

Our comprehensive package of sampling accessories for measuring solid and liquid samples provide you the utmost utility right out of the box.

QUANTITATIVE:

Our state of the art BWIQ^® Raman data analysis software package provides an intuitive user interface, intelligent algorithms, and efficient matrix calculation power, making it easy to use by both expert and novice users to develop quantitative and qualitative chemometric models.

FEATURES

Patented CleanLaze^® Technology for Laser Stabilization
Rayleigh line cut-off at 65 cm^-1
Fiber Optic Coupling for Convenient Sampling

ACCESSORIES (Included):

Fiber-optic Raman trigger probes
Laser safety goggles

ACCESSORIES (Optional):

Battery
Cuvette holder
Tablet holder
A range of long working distance lenses (up to 6 meters)
Probe holder and XYZ positioning stage
Industrial Raman immersion probe shaft
Video microscope
Performance testing kit, including liquid vial holder
Raman flow cell
BWID® acquisition and identification software

The NanoRam is a state-of-the-art handheld Raman instrument for nondestructive identification and verification of materials such as APIs, excipients, intermediates, & finished products. Compact and agile, the NanoRam can be used by non-technical users to rapidly identify samples in the lab, warehouse, loading dock or field, helping to eliminate quarantine areas and expedite materials through the manufacturing lifecycle. Utilizing Raman technology, non-contact analysis can be performed through transparent containers, all while maintaining the volume and integrity of the sample.

The NanoRam handheld Raman spectrometer facilitates fast and convenient transitions between sampling accessories for raw material identification through a variety of packaging. The NanoRam comes standard with the point and shoot, vial holder, bottle adaptor, and immersion probe accessories for optimal identification of different sample forms. These accessories allow you to measure through plastic and glass containers, take in situ measurements of liquids and powders, and measure larger containers only accessible from the top. Additionally, right angle, and tablet holder accessories are available to facilitate hands-free sampling . The NanoRam is operated with easy to follow, touch screen NanoRam OS (NOS) embedded software, which allows for identification and verification and library and method development. The NanoRam ID (NID) PC software provides a secure database for data and methods management, allowing customers to export data, generate and e-sign reports and transfer methods and libraries to other NanoRam units.

Raman spectroscopy is an approved method by the U.S. and European Pharmacopoeia, as well as the Pharmacopoeia of the People’s Republic of China. It is also a well-recognized method for compliance with the PIC/S GMP guide regarding 100% identity assurance for starting materials. NanoRam has performance validation tests to ensure system performance to the standards of the USP<858>, EP 2.2.48 and JP 2.26. The NanoRam is fully compliant with all governing regulations, including 21 CFR Part 11 and Part 1040.10, and can play an integral role in cGMP compliant facilities. B&W Tek offers a wide variety of services, including assistance with method and/or new library development as well as support with IQ/OQ/PQ implementation.

Intuitive Software – a user-friendly interface for both technical & non-technical users to make their job easier
Versatility – measure a variety of samples in a variety of environments and packaging with just one unit
Data Reproducibility – superior hardware ensures that results are consistent and reliable
Performance – robust multivariate algorithms guarantee accuracy when testing and identifying materials

Features:

• High-Brightness Touch Screen Display
• Embedded 1 & 2 Dimensional Barcode Scanner
• IP-64 Dust Tight and Splash Proof Rated Housing
• Sampling Accessories for Almost Any Environment
• Batch Scanning Option for Large Volume Operation
• Intuitive Software for Technical & Non-technical Users
• Wi-Fi & Ethernet Communication for Data Sync & Management

Easy Operation for Non-Technical Users:

• Touch screen interface with simple 1 touch workflow
• Easy single-handed operation
• Batch mode for quick testing of multiple containers
• Interface available in multiple languages
• Barcode scanner for quick method selection
• Compatible with Labware LIMS